ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ig heavy chain V region 36-65

Intramolecular
Cysteine 21 and cysteine 95
A redox-regulated disulphide may form within Ig heavy chain V region 36-65 between cysteines 21 and 95 (322 and 396 respectively in this structure).

Details

Redox score ?
80
PDB code
1jfq
Structure name
antigen-binding fragment of the murine anti-phenylarsonate antibody 36-71, "fab 36-71"
Structure deposition date
2001-06-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01747
Residue number A
21
Residue number B
95
Peptide name
Ig heavy chain V region 36-65

Ligandability

Cysteine 21 of Ig heavy chain V region 36-65

Cysteine 95 of Ig heavy chain V region 36-65

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